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Genetic element (GENE)
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BCH-GENE-SCBD-111880-2   |   PDF   |   Print   |  
 
published: 21 Mar 2017 last updated: 16 May 2017
General information
Lac operon repressor gene
EN
CS-lacI-ECOLX
EN
Protein coding sequence
No
Donor organism
EN
Characteristics of the protein coding sequence
Lactose operon repressor
EN
The lactose operon repressor is a DNA binding protein that functions to regulate the expression of the Lac operon.

In the absence of lactose it inhibits the expression of the genes lacZ-lacY-lacA which code for the lactose-degrading enzymes of the operon by binding to the operator region of the Lac operon, thus hindering RNA polymerase from binding to the Lac promoter.

The repressor is inactivated by lactose which binds to the repressor. This causes a confomational change that prevents it from binding to the operator region.
EN
Additional Information
EN
Records referencing this document Show in search
Record type Field Record(s)
Living Modified Organism Introduced or modified genetic element(s) 1